If you decide to go ahead with removing fillers, here’s a general idea of what to expect:

It’s generally safe to have lip fillers dissolved by a Doctor or Nurse Practitioner

Still, as with any procedure, you’ll want to keep a few potential risks in mind.

There’s a small chance hyaluronidase will cause an allergic reaction. According to 2020 researchTrusted Source, the risk of allergic reactions is typically very low: between 0.05 percent to 0.69 percent. Fewer than 0.1 percent of people experience itching and swelling.

That said, you have a greater chance of an allergic reaction with a dose of more than 100,000 IU. The rate of allergic reactions increases to just over 31 percent with a dose of 200,000 IU.

Hyaluronidase may also interact with certain medications, including some anxiety medications and antihistamines.

Another potential side effect to consider: Hyaluronidase could potentially break down too much of the filler, as well as your body’s own HA. Consequently, you might lose more volume than you want and notice some unevenness in your lips. Your body will eventually produce more HA, but this can take a few months.

It’s important to tell your provider about any underlying medical conditions you have before getting HA fillers. This procedure may not be appropriate if you:

• have a history of blood-clotting issues
• smoke
• have diabetes
• currently take immunosuppressive medications
• are going through an active oral herpes infection
• are pregnant or nursing

Even good candidates for HA lip injections may experience side effects from this cosmetic procedure. Speak with your provider about all of the possible risks before getting treatment.

Common side effects

Common side effects of HA lip fillers include:

• temporary redness or purplish tone, and swelling of the lips
• mild bruising and bleeding around the injection sites
• temporary bumps or lumps that may arise around the injection sites

Any temporary pain or swelling usually goes away within 1 to 2 days after your procedure.

Uncommon side effects that should be seen by a doctor

You should report the following uncommon, but potentially serious side effects of HA injections to your doctor right away:

• blisters around the lips
• numbness or bluish coloring of the lips
• severe swelling that won’t go away
• vision changes
• symptoms of an infection, like increased swelling, pigment changes, and drainage